LabCorp and its Specialty Testing Group, a fully integrated portfolio of specialty and esoteric testing laboratories.

Syphilis

Fundamental prevention

There is a troubling rise in syphilis among women and newborns in the United States.1 The CDC reported that during 2015-2016 overall rate of syphilis in the US increased by 18%.1 Rates of primary and secondary infection among women increased by 36%. Increasing rates of syphilis among women has led to a steep rise in congenital syphilis. Congenital syphilis is preventable through routine screening and timely treatment.1

ACOG guidelines recommend screening for syphilis women who are sexually active, and those who are at higher risk including women with a history of sexually transmitted infections, drug use, multiple or concurrent partners, adolescents who exchange sex for drugs or money, use intravenous drugs, are entering a detention facility,2 or live in a high-prevalence area.3

Diagnosing syphilis is more commonly made using two types of blood tests: nontreponemal tests and treponemal tests. Both tests are needed to confirm a diagnosis of syphilis.4 LabCorp offers two testing options:

Testing Options

012005 Rapid Plasma Reagin (RPR) test with Reflex to Quantitative RPR and Confirmatory Treponema pallidum Antibodies

 

RPR Algorithm

 

082345 Treponema pallidum (Syphilis) Screening Cascade

 

T-pallidum Algorithm

 

For more information, please download the following brochure:

Women’s Health Syphilis

Reference

  1. Centers for Disease Control and Prevention. CDC Fact Sheet: Reported STDs in the United States, 2016. Atlanta, GA: Centers for Disease Control and Prevention, US Dept of Health and Human Services; Sept 2017
  2. American College of Obstetricians and Gynecologists. Well Women Recommendations. High-Risk Factors. Available at: https://www.acog.org/About-ACOG/ACOG-Departments/Annual-Womens-Health-Ca...
  3. American College of Obstetricians and Gynecologists. Clinical Practice: Syphilis resurgence reminds us of the importance of STD screening and treatment during prenatal care. https://www.acog.org/About-ACOG/ACOG-Departments/ACOG-Rounds/May-2017/Sy...
  4. Centers for Disease Control and Prevention. Syphilis – CDC Fact Sheet (Detailed). Atlanta, GA: Centers for Disease Control and Prevention, US Dept of Health and Human Services; 2017. https://www.cdc.gov/std/syphilis/stdfact-syphilis-detailed.htm; last updated: February 13, 2017. Accessed January 3, 2018